The Importance of GLS Evaluation in MR Diagnosis

Oct 13, 2025 by windailys.com 82 views

The Global Longitudinal Strain (GLS) Relationship of Preoperative Left Ventricle to Major Cardiovascular Events (KKVM) During Nursing and Fraction of Left Ventricular Ejection Post -Mitral Valve Operations in Weight Mitral Regurgitation Patients in Adam Malik Hospital Medan Medan

Introduction

Mitral regurgitation (MR) is a significant cause of heart valve disorders, particularly in developing countries. Unaddressed severe MR conditions can increase the risk of death and other serious complications. This study aims to determine the relationship between the Global Longitudinal Strain (GLS) of the left ventricle measured before surgery with the incidence of major cardiovascular (KKVM) and the Post -Surgive Left Ventricular Ejection Fraction (FEVK) in patients undergoing the procedure for repairing the mitral valve.

The Importance of Mitral Regurgitation (MR) Diagnosis and Treatment

Mitral regurgitation is a condition where the mitral valve does not close properly, allowing blood to flow backward into the left atrium. This can lead to increased pressure on the left atrium and eventually cause heart failure. Severe MR can also increase the risk of stroke, heart attack, and other cardiovascular complications. Early diagnosis and treatment of MR are crucial to prevent these complications and improve patient outcomes.

The Role of Global Longitudinal Strain (GLS) in MR Diagnosis

Global Longitudinal Strain (GLS) is an important parameter in echocardiography that can provide more in-depth information about the left ventricular contractile function. Decreased GLS value is often directly proportional to the degree of myocardial damage and can be used to estimate the overall heart function. In the context of severe MR, GLS monitoring can help doctors in deciding more precise treatment tactics and prepare mitigation steps for the risk of complications during and after surgical procedures.

Methodology

This study is an ambitional observational analysis involving 40 patients with severe MR undergoing mitral valve operations at Adam Malik Hospital Medan between January 2021 and October 2023. The diagnosis of severe MR is based on the American Society of Echocardiography (ASE) guidelines. Bivariate analysis is carried out to investigate the relationship between preoperative left ventricle GLS and KKVM and FEVK events during postoperative care, with a p value <0.05 is considered significant.

Research Result

Of the 40 research subjects, 16 of them are men (40%). The average preoperative left ventricular GLS value is -18.12% ± 5.79. During the postoperative care period, 3 patients (7.5%) died due to cardiovascular complications, and 14 patients (35%) experienced acute heart failure. The average postoperative FEVK is 38.71% ± 12.58. Through Chi-Square analysis, it was found that the preoperative left ventricular GLS value ≤ -17.1% was significantly related to the events of KKVM and FEVK during postoperative care, with ODDS ratio (OR) successively 0.134 and 1.85 (p <0, 05).

Analysis and Discussion

The results showed that there was a significant relationship between the preoperative left ventricular GLS and major cardiovascular events and the postoperative ejection fraction. This indicates that GLS assessment before surgery can function as an effective predictor to identify the risk of postoperative complications in patients with severe MR.

The Importance of GLS Evaluation in MR Diagnosis

GLS evaluation is a valuable diagnostic tool in the diagnosis of MR. Through an earlier introduction to patients who are at high risk of experiencing complications, the medical team can take a more proactive and directed therapeutic approach, which in turn will improve the clinical outcome and quality of life of the patient.

Conclusion

This study confirms the importance of GLS evaluation as a valuable diagnostic tool before intervening with patients with severe MR. The results of this study can motivate further research in the field of cardiology and improve patient care standards throughout the world.

Recommendations

Based on the results of this study, the following recommendations are made:

GLS evaluation should be performed before surgery in patients with severe MR to identify those at high risk of postoperative complications.
Patients with a preoperative left ventricular GLS value ≤ -17.1% should be considered for closer monitoring and more aggressive treatment during and after surgery.
Further research is needed to investigate the relationship between GLS and other cardiovascular events in patients with severe MR.

Limitations of the Study

This study has several limitations, including:

The small sample size of the study.
The study was conducted in a single hospital, which may limit the generalizability of the results.
The study did not investigate the relationship between GLS and other cardiovascular events in patients with severe MR.

Future Research Directions

Future research should focus on investigating the relationship between GLS and other cardiovascular events in patients with severe MR. Additionally, further research is needed to investigate the use of GLS evaluation in the diagnosis and treatment of MR.

Conclusion

In conclusion, this study confirms the importance of GLS evaluation as a valuable diagnostic tool before intervening with patients with severe MR. The results of this study can motivate further research in the field of cardiology and improve patient care standards throughout the world.
Frequently Asked Questions (FAQs) About Global Longitudinal Strain (GLS) and Mitral Regurgitation (MR)

Q: What is Global Longitudinal Strain (GLS)?

A: Global Longitudinal Strain (GLS) is an important parameter in echocardiography that can provide more in-depth information about the left ventricular contractile function. It measures the percentage of shortening or lengthening of the left ventricle in the longitudinal direction.

Q: How is GLS related to mitral regurgitation (MR)?

A: GLS is an important tool in the diagnosis and treatment of MR. A decreased GLS value is often directly proportional to the degree of myocardial damage and can be used to estimate the overall heart function. In the context of severe MR, GLS monitoring can help doctors in deciding more precise treatment tactics and prepare mitigation steps for the risk of complications during and after surgical procedures.

Q: What is the significance of GLS value ≤ -17.1% in patients with severe MR?

A: The GLS value ≤ -17.1% is a significant indicator of increased risk of postoperative complications in patients with severe MR. Patients with this value should be considered for closer monitoring and more aggressive treatment during and after surgery.

Q: What are the limitations of this study?

A: This study has several limitations, including:

The small sample size of the study.
The study was conducted in a single hospital, which may limit the generalizability of the results.
The study did not investigate the relationship between GLS and other cardiovascular events in patients with severe MR.

Q: What are the recommendations based on the results of this study?

A: Based on the results of this study, the following recommendations are made:

GLS evaluation should be performed before surgery in patients with severe MR to identify those at high risk of postoperative complications.
Patients with a preoperative left ventricular GLS value ≤ -17.1% should be considered for closer monitoring and more aggressive treatment during and after surgery.
Further research is needed to investigate the relationship between GLS and other cardiovascular events in patients with severe MR.

Q: What are the future research directions?

A: Future research should focus on investigating the relationship between GLS and other cardiovascular events in patients with severe MR. Additionally, further research is needed to investigate the use of GLS evaluation in the diagnosis and treatment of MR.

Q: How can GLS evaluation improve patient care standards?

A: GLS evaluation can improve patient care standards by providing an earlier introduction to patients who are at high risk of experiencing complications. This can lead to a more proactive and directed therapeutic approach, which in turn will improve the clinical outcome and quality of life of the patient.

Q: What are the implications of this study for clinical practice?

A: This study has significant implications for clinical practice, particularly in the diagnosis and treatment of MR. GLS evaluation should be performed before surgery in patients with severe MR to identify those at high risk of postoperative complications.

Q: What are the potential benefits of GLS evaluation in patients with severe MR?

A: The potential benefits of GLS evaluation in patients with severe MR include:

Improved diagnosis and treatment of MR.
Reduced risk of postoperative complications.
Improved clinical outcome and quality of life of the patient.

Q: What are the potential risks of GLS evaluation in patients with severe MR?

A: The potential risks of GLS evaluation in patients with severe MR include:

False-negative results, which may lead to delayed diagnosis and treatment.
False-positive results, which may lead to unnecessary treatment and complications.
Radiation exposure from echocardiography.

Q: How can healthcare providers ensure the accuracy and reliability of GLS evaluation?

A: Healthcare providers can ensure the accuracy and reliability of GLS evaluation by:

Using high-quality echocardiography equipment.
Performing GLS evaluation by experienced and trained healthcare providers.
Interpreting GLS results in the context of the patient's overall clinical presentation and medical history.