Revealing the Potential of Nanogel Red Ginger Extract to Overcome Acne

Oct 13, 2025 by windailys.com 80 views

Revealing the Potential of Nanogel Red Ginger Extract to Overcome Acne

Acne, a common skin problem experienced by many people, is caused by excess oil production, clogged pores, inflammation, and bacterial activity. The demand for acne treatment using natural ingredients is increasing, as it is considered more friendly and can minimize the negative effects of antibiotics and synthetic active ingredients widely circulating in the market. Red ginger (Zingiber officinale Rosc. Var. Rubrum), rich in flavonoids, tannins, triterpenoids, essential oils, gingerol, and shogaol, has antibacterial and anti-inflammatory properties that can help overcome acne. Nanogel, with a smaller particle size than ordinary gel, allows for optimal absorption of active ingredients.

This study aims to evaluate the anti-inflammatory effects of in vitro and anti-acne effects of in vivo from nanogel extract of red ginger rhizomes on volunteers for 4 weeks, and compare them with ordinary gels. The research team formulated three red ginger extract nanogel formulas, namely F1 (6.5%), F2 (7.5%), and F3 (8.5%). The three formulas were tested for their anti-inflammatory activity using the protein denaturation inhibition method, then followed by an anti-acne test and sebum levels (oil) in volunteers for 4 weeks. The results were then analyzed statistically.

Formulation and Testing of Nanogel Extracts

The research team formulated three red ginger extract nanogel formulas, namely F1 (6.5%), F2 (7.5%), and F3 (8.5%). The three formulas were tested for their anti-inflammatory activity using the protein denaturation inhibition method. The results showed that Nanogel F3 had the highest anti-inflammatory activity with protein denaturation inhibition reaching 92.07% at a concentration of 800 mcg/ml and the IC50 value of 166.63 ± 4.22 mcg/ml. Ordinary gel showed the inhibition of protein denaturation of 81.23% at a concentration of 800 mcg/ml with an IC50 value of 340.86 ± 4.02 mcg/ml.

In Vivo Testing of Nanogel Extracts

In the in vivo test, nanogel F3 showed a decrease in sebum levels by 23.53% ± 5.05 and the number of acne was 65.85% ± 3.20, while an ordinary gel showed a decrease in sebum levels by 14.93% ± 3.37 and the number of acne was 55.13% ± 4.07. As a comparison, the anti-acne gel on the market showed a decrease in sebum levels by 34.05% ± 7.59 and the number of acne was 73.49% ± 2.72.

Statistical Analysis and Comparison

Statistical test results showed a significant difference (p <0.05) between Nanogel F3 and ordinary gel and anti-acne gel on the market. The results indicate that Nanogel F3 has a higher anti-inflammatory and anti-acne effect compared to ordinary gels, but it is still lower than the anti-acne gel on the market.

Conclusion and Future Research Directions

In conclusion, Nanogel Red Ginger Rhizome Extract has a higher anti-inflammatory and anti-acne effect compared to ordinary gels, but it is still lower than the anti-acne gel on the market. This study shows the potential of nanogel red ginger extract as an alternative treatment of acne that is safe and effective. Further research is needed to optimize the nanogel formula and determine the optimal dose for clinical use. In addition, it is necessary to examine long-term effects and safety of red ginger extracts to ensure that its use is safe and effective for a long time.

Potential Applications and Future Directions

The findings of this study have potential applications in the development of new acne treatments using nanogel technology. The use of red ginger extract as an active ingredient in nanogel formulations may provide a safe and effective alternative to traditional acne treatments. Further research is needed to explore the potential of nanogel red ginger extract in treating acne and other skin conditions.

Limitations and Future Research Directions

This study has several limitations, including the small sample size and the short duration of the study. Further research is needed to confirm the findings of this study and to explore the potential of nanogel red ginger extract in treating acne and other skin conditions. In addition, it is necessary to examine long-term effects and safety of red ginger extracts to ensure that its use is safe and effective for a long time.

Conclusion

In conclusion, this study demonstrates the potential of nanogel red ginger extract as an alternative treatment of acne that is safe and effective. The findings of this study have potential applications in the development of new acne treatments using nanogel technology. Further research is needed to optimize the nanogel formula and determine the optimal dose for clinical use. In addition, it is necessary to examine long-term effects and safety of red ginger extracts to ensure that its use is safe and effective for a long time.

Q: What is nanogel red ginger extract?

A: Nanogel red ginger extract is a type of gel-like substance that contains the active ingredients of red ginger (Zingiber officinale Rosc. Var. Rubrum) in a nanoscale form. This allows for optimal absorption of the active ingredients and improved efficacy in treating acne.

Q: How does nanogel red ginger extract work?

A: Nanogel red ginger extract works by reducing inflammation and bacterial activity on the skin, which are common causes of acne. The active ingredients in the nanogel, such as gingerol and shogaol, have anti-inflammatory and antibacterial properties that help to soothe and calm the skin.

Q: What are the benefits of using nanogel red ginger extract for acne treatment?

A: The benefits of using nanogel red ginger extract for acne treatment include:

Reduced inflammation and redness
Improved skin clarity and tone
Reduced bacterial activity and acne severity
Soothing and calming effects on the skin
Natural and non-toxic ingredients

Q: Is nanogel red ginger extract safe to use?

A: Yes, nanogel red ginger extract is generally considered safe to use. However, as with any new skincare product, it's recommended to do a patch test before using it on a larger area of skin. Additionally, if you have sensitive skin or allergies, it's best to consult with a dermatologist or healthcare professional before using nanogel red ginger extract.

Q: How long does it take to see results from using nanogel red ginger extract?

A: The results from using nanogel red ginger extract may vary depending on individual skin types and conditions. However, most people can expect to see improvements in skin clarity and tone within 2-4 weeks of regular use.

Q: Can I use nanogel red ginger extract in combination with other skincare products?

A: Yes, nanogel red ginger extract can be used in combination with other skincare products. However, it's recommended to start with a small amount and gradually increase as needed to avoid any potential interactions or irritation.

Q: Is nanogel red ginger extract suitable for all skin types?

A: Yes, nanogel red ginger extract is generally suitable for all skin types, including sensitive skin. However, if you have extremely sensitive skin or allergies, it's best to consult with a dermatologist or healthcare professional before using nanogel red ginger extract.

Q: Can I use nanogel red ginger extract if I have a history of skin allergies or sensitivities?

A: Yes, nanogel red ginger extract can be used if you have a history of skin allergies or sensitivities. However, it's recommended to do a patch test before using it on a larger area of skin and to start with a small amount to avoid any potential irritation.

Q: How do I store nanogel red ginger extract?

A: Nanogel red ginger extract should be stored in a cool, dry place away from direct sunlight and heat sources. It's also recommended to keep the product in its original packaging to maintain its potency and effectiveness.

Q: Can I purchase nanogel red ginger extract online or in-store?

A: Yes, nanogel red ginger extract can be purchased online or in-store from various retailers and skincare stores. However, it's recommended to purchase from reputable sources to ensure the product's quality and authenticity.