Journal of Cosmetic Dermatology

Oct 13, 2025 by windailys.com 71 views

Introduction

In the realm of cosmetics, moisturizers play a vital role in hydrating the skin, reducing water evaporation, and attracting moisture from the air. Among various moisturizers, jojoba oil, derived from the seeds of the simmondsia chinensis plant, has gained significant attention due to its rich content of vitamin E, vitamin B complexes, and fatty acids such as palmitic acid, palmitoleic, stearic, and oleic. The presence of these nutrients makes jojoba oil an excellent ingredient for maintaining skin moisture. On the other hand, nanocrim is a cutting-edge delivery system technology that accelerates the absorption of active substances due to its extremely small size. This study aims to formulate stable nanocrim preparations containing jojoba oil and evaluate their moisturizing properties.

Research Purposes

The primary objective of this study is to formulate stable nanocrim preparations that meet physical quality standards and compare their moisturizing properties with cream preparations containing jojoba oil. By achieving this goal, we can determine the efficacy of nanocrim as a delivery system for jojoba oil and its potential as a moisturizer.

Methodology

To formulate the nanocrim preparations, we used high stirring methods and tween 80 as surfactants. The concentration of jojoba oil in the preparations was varied at 2.5% (F1), 5% (F2), and 7.5% (F3). The quality of the preparations was tested through stability testing at room temperature, cyclic tests, homogeneity, emulsion type, pH, scatter power, viscosity, centrifugation, transmittance, surface tension, and particle size. Additionally, irritation testing and comparison of the effectiveness of nanocrim moisturizing jojoba oil with cream containing jojoba oil were conducted.

Research Results

The results of this study showed that the resulting nanocrim preparations were yellow and thick, stable organoleptically in terms of aroma, shape, and color at room temperature for 12 weeks. The preparations were also stable in cyclic testing and centrifugation. The particle size of the nanocrim preparations obtained was F1 118.15 Nm, F2 141.39 Nm, and F3 160.23 Nm, which falls within the nanocrim range of 20 to 500 nm. The quality testing results revealed that the nanocrim preparations were homogeneous, met the criteria for pH, viscosity, spread power, and were classified as oil-in-water emulsions. In transmittance testing, both nanocrim and cream preparations showed a percentage value between 90-100%, with a clear and transparent visual display. The measurement of surface tension obtained ranges from 35.6 dyne/cm to 47.4 dyne/cm.

Conclusion

The results of this study demonstrate that jojoba oil can be formulated in nanocrim as a moisturizer, and nanocrim containing 7.5% of jojoba oil shows better moisturizing activities in increasing water content compared to 2.5%, 5%, and 7.5% cream concentrations. This is attributed to the smaller particle size of the nanocrim, which allows for more efficient absorption. With these findings, nanocrim jojoba oil emerges as an interesting alternative for effective and efficient skin care.

Useful Resources

Journal of Cosmetic Dermatology: Articles about the use of jojoba oil in cosmetic formulations.
International Journal of Pharmaceutics: Publication about nanotechnology technology in health and beauty products.
Cosmetics and Toiletries: Sources of information about the development of cosmetic products, including stability and effectiveness tests.

Future Directions

This study provides a foundation for further research on the use of nanocrim as a delivery system for jojoba oil and its potential applications in skin care. Future studies can explore the effects of varying concentrations of jojoba oil on the moisturizing properties of nanocrim preparations and investigate the stability of nanocrim preparations over extended periods. Additionally, the development of nanocrim preparations containing other active ingredients can be explored to create a range of cosmetic products with enhanced moisturizing properties.

Limitations

This study has several limitations that should be acknowledged. Firstly, the study was conducted in a controlled laboratory setting, and the results may not be directly applicable to real-world scenarios. Secondly, the study focused on the moisturizing properties of nanocrim preparations containing jojoba oil, and further research is needed to explore the effects of other active ingredients on the stability and effectiveness of nanocrim preparations. Finally, the study did not investigate the potential toxicity or adverse effects of nanocrim preparations, which should be addressed in future studies.

Conclusion

In conclusion, this study demonstrates the potential of nanocrim as a delivery system for jojoba oil and its applications in skin care. The results of this study provide a foundation for further research on the use of nanocrim and its potential applications in the development of cosmetic products. By addressing the limitations of this study and exploring new avenues of research, we can create a range of cosmetic products with enhanced moisturizing properties and improved stability.

Q: What is nanocrim, and how does it work as a delivery system for jojoba oil?

A: Nanocrim is a cutting-edge delivery system technology that accelerates the absorption of active substances due to its extremely small size. It works by encapsulating the jojoba oil in tiny particles, allowing for more efficient absorption and increased moisturizing properties.

Q: What are the benefits of using jojoba oil as a moisturizer?

A: Jojoba oil is rich in vitamin E, vitamin B complexes, and fatty acids, making it an excellent ingredient for maintaining skin moisture. It also has anti-inflammatory and antioxidant properties, which can help to soothe and protect the skin.

Q: How does the concentration of jojoba oil affect the moisturizing properties of nanocrim preparations?

A: The results of this study showed that nanocrim preparations containing 7.5% of jojoba oil showed better moisturizing activities in increasing water content compared to 2.5%, 5%, and 7.5% cream concentrations. This is attributed to the smaller particle size of the nanocrim, which allows for more efficient absorption.

Q: What are the limitations of this study, and how can they be addressed in future research?

A: This study has several limitations, including the controlled laboratory setting and the focus on the moisturizing properties of nanocrim preparations containing jojoba oil. Future research should aim to explore the effects of other active ingredients on the stability and effectiveness of nanocrim preparations and investigate the potential toxicity or adverse effects of nanocrim preparations.

Q: What are the potential applications of nanocrim preparations containing jojoba oil in skin care?

A: The results of this study demonstrate the potential of nanocrim as a delivery system for jojoba oil and its applications in skin care. Nanocrim preparations containing jojoba oil can be used as a moisturizer, anti-aging product, or skin protectant, and can be formulated into a range of cosmetic products, including creams, lotions, and serums.

Q: How can nanocrim preparations containing jojoba oil be stabilized and preserved for extended periods?

A: The results of this study showed that nanocrim preparations containing jojoba oil were stable in cyclic testing and centrifugation, and had a particle size within the nanocrim range of 20 to 500 nm. To stabilize and preserve nanocrim preparations, it is recommended to use a combination of surfactants and preservatives, and to store the preparations in a cool, dry place.

Q: What are the potential risks or side effects of using nanocrim preparations containing jojoba oil?

A: The potential risks or side effects of using nanocrim preparations containing jojoba oil are not well understood and require further research. However, it is recommended to conduct thorough safety testing and to follow good manufacturing practices to minimize the risk of adverse effects.

Q: How can nanocrim preparations containing jojoba oil be formulated into a range of cosmetic products?

A: Nanocrim preparations containing jojoba oil can be formulated into a range of cosmetic products, including creams, lotions, serums, and masks. The formulation process involves mixing the nanocrim preparation with other ingredients, such as emollients, humectants, and preservatives, to create a stable and effective product.

Q: What are the future directions for research on nanocrim preparations containing jojoba oil?

A: Future research should aim to explore the effects of varying concentrations of jojoba oil on the moisturizing properties of nanocrim preparations, investigate the stability of nanocrim preparations over extended periods, and develop nanocrim preparations containing other active ingredients. Additionally, the development of nanocrim preparations for specific skin types or conditions, such as acne or rosacea, should be explored.