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Oct 13, 2025 by windailys.com 115 views

The Relationship of Increased Levels of Fasting Blood Glucose with Clinical Events of Major Cardiovascular During Treatment in Hospitals in Patients with Acute Coronary Syndrome Without Diabetes in the Adam Malik Hajj General Hospital Medan

Background and Importance of the Study

Acute coronary syndrome (SKA) is a serious condition that occurs when blood flow to the heart is inhibited, often accompanied by an increase in blood glucose levels. This condition is a common metabolic disorder in SKA sufferers, and increased blood glucose levels are associated with an increased risk of complications during treatment in hospitals. However, there are still a few studies that examine the relationship between increased levels of fasting blood glucose and clinical events of major cardiovascular (KKVM) in patients with SKA without diabetes. Understanding this relationship is crucial for developing effective treatment strategies and improving patient outcomes.

Objective of the Study

This study aims to examine the relationship between fasting blood glucose levels (kgd fasting) with major cardiovascular clinical events (KKVM) in patients with SKA Nondiabetics during hospital treatment. The primary objective is to identify the association between fasting blood glucose levels and the risk of KKVM in patients with SKA without diabetes.

Methodology

This study was conducted retrospectively involving 117 Nondiabetes patients treated at the Adam Malik Hajj General Hospital in Medan with a SKA diagnosis in 2014. Patients were grouped based on the level of fasting, which was less than 110 mg/dl (n = 64) and more than 110 mg/dl (n = 53). Multivariate logistics regression analysis is used to assess the relationship between KGD fasting and KKVM during hospital treatment. The study design and methodology are crucial for ensuring the accuracy and reliability of the results.

Results of the Study

The results showed that 64 (54.7%) of 117 Nondiabetes patients with SKA experienced KKVM during hospital treatment. The KKVM incidence is higher in groups of patients with an increase in fasting KGD compared to normal fasting KGD groups (60.9% vs 39.1%, p <0.001). Nevertheless, only the incidence of heart failure and mortality that shows statistical significance based on the value of KGD fasting. Multivariate analysis shows that high fasting KGD is associated with an increase in KKVM risk in hospitals in SKA Nondiabetic patients (OR: 4,78; 95% CI: 2.09-10.92). The results of the study provide valuable insights into the relationship between fasting blood glucose levels and the risk of KKVM in patients with SKA without diabetes.

Conclusion and Implications

This study shows that an increase in fasting KGD is associated with an increased risk of KKVM during treatment in hospitals and can be an independent predictor for KKVM (death or heart failure) during hospital treatment in SKA Nondiabetic patients. The findings of the study have significant implications for the management of patients with SKA without diabetes, highlighting the importance of monitoring and controlling blood glucose levels.

Additional Analysis and Explanation

The results of this study provide additional evidence about the importance of controlling blood glucose levels in SKA patients, even in those who do not suffer from diabetes. An increase in fasting KGD can be an early sign of metabolic disorders that can worsen the heart condition and increase the risk of complications. It is essential for medical personnel to monitor blood glucose levels regularly in SKA patients, both diabetes and those who are not, and to implement the right strategy to control blood glucose levels in an effort to prevent or reduce the risk of KKVM.

Recommendations for Future Research and Practice

It is necessary to do further research with a larger number of samples and longer observation periods to confirm the results of this study.
Health education and promotion efforts are needed to increase public awareness about the importance of blood glucose control, especially in SKA sufferers.
It is necessary to develop a comprehensive treatment protocol for managing blood glucose levels in SKA patients, both diabetes and those who do not, in order to minimize the risk of KKVM.

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Limitations of the Study

This study has several limitations, including the small sample size and the retrospective design. However, the study provides valuable insights into the relationship between fasting blood glucose levels and the risk of KKVM in patients with SKA without diabetes.

Future Directions for Research

Future studies should aim to confirm the results of this study using larger sample sizes and longer observation periods. Additionally, studies should investigate the mechanisms underlying the association between fasting blood glucose levels and the risk of KKVM in patients with SKA without diabetes.

Conclusion

In conclusion, this study shows that an increase in fasting KGD is associated with an increased risk of KKVM during treatment in hospitals and can be an independent predictor for KKVM (death or heart failure) during hospital treatment in SKA Nondiabetic patients. The findings of the study have significant implications for the management of patients with SKA without diabetes, highlighting the importance of monitoring and controlling blood glucose levels.
Frequently Asked Questions (FAQs) About the Relationship Between Fasting Blood Glucose Levels and Clinical Events of Major Cardiovascular in Patients with Acute Coronary Syndrome Without Diabetes

Q: What is acute coronary syndrome (SKA)?

A: Acute coronary syndrome (SKA) is a serious condition that occurs when blood flow to the heart is inhibited, often accompanied by an increase in blood glucose levels. This condition is a common metabolic disorder in SKA sufferers.

Q: What is the relationship between fasting blood glucose levels and clinical events of major cardiovascular in patients with SKA without diabetes?

A: The results of this study show that an increase in fasting blood glucose levels is associated with an increased risk of clinical events of major cardiovascular in patients with SKA without diabetes. High fasting blood glucose levels can be an independent predictor for clinical events of major cardiovascular, such as death or heart failure, during hospital treatment in SKA Nondiabetic patients.

Q: What are the implications of this study for the management of patients with SKA without diabetes?

A: The findings of this study highlight the importance of monitoring and controlling blood glucose levels in patients with SKA without diabetes. Medical personnel should regularly monitor blood glucose levels in SKA patients, both diabetes and those who are not, and implement the right strategy to control blood glucose levels in an effort to prevent or reduce the risk of clinical events of major cardiovascular.

Q: What are the limitations of this study?

A: This study has several limitations, including the small sample size and the retrospective design. However, the study provides valuable insights into the relationship between fasting blood glucose levels and the risk of clinical events of major cardiovascular in patients with SKA without diabetes.

Q: What are the recommendations for future research and practice?

A: It is necessary to do further research with a larger number of samples and longer observation periods to confirm the results of this study. Health education and promotion efforts are needed to increase public awareness about the importance of blood glucose control, especially in SKA sufferers. It is necessary to develop a comprehensive treatment protocol for managing blood glucose levels in SKA patients, both diabetes and those who do not, in order to minimize the risk of clinical events of major cardiovascular.

Q: What are the potential mechanisms underlying the association between fasting blood glucose levels and the risk of clinical events of major cardiovascular in patients with SKA without diabetes?

A: The exact mechanisms underlying the association between fasting blood glucose levels and the risk of clinical events of major cardiovascular in patients with SKA without diabetes are not fully understood. However, it is possible that high fasting blood glucose levels may contribute to the development of insulin resistance, inflammation, and oxidative stress, which can worsen the heart condition and increase the risk of clinical events of major cardiovascular.

Q: How can healthcare providers implement the findings of this study in clinical practice?

A: Healthcare providers can implement the findings of this study by regularly monitoring blood glucose levels in SKA patients, both diabetes and those who are not, and implementing the right strategy to control blood glucose levels in an effort to prevent or reduce the risk of clinical events of major cardiovascular. Additionally, healthcare providers can develop a comprehensive treatment protocol for managing blood glucose levels in SKA patients, both diabetes and those who do not, in order to minimize the risk of clinical events of major cardiovascular.

Q: What are the potential benefits of controlling blood glucose levels in patients with SKA without diabetes?

A: Controlling blood glucose levels in patients with SKA without diabetes may help to reduce the risk of clinical events of major cardiovascular, such as death or heart failure, during hospital treatment. Additionally, controlling blood glucose levels may help to improve the overall quality of life and reduce the risk of long-term complications in patients with SKA without diabetes.

Q: What are the potential risks of not controlling blood glucose levels in patients with SKA without diabetes?

A: Not controlling blood glucose levels in patients with SKA without diabetes may increase the risk of clinical events of major cardiovascular, such as death or heart failure, during hospital treatment. Additionally, not controlling blood glucose levels may lead to long-term complications, such as kidney disease, nerve damage, and vision loss, in patients with SKA without diabetes.