Correlation between the Depth of STE Depression and the Anterior Left Artery Stenosis in Patients with Acute Myocardial Infarction

Oct 13, 2025 by windailys.com 17 views

Correlation between the Depth of STE Depression and the Anterior Left Artery Stenosis in Patients with Acute Myocardial Infarction

Introduction

Acute myocardial infarction with ST (IMAEST) segment elevation is a medical condition that requires immediate attention. One indicator that can help in the diagnosis and treatment is the presence of St Precordial Depression in the Electrocardiogram (ECG). Research shows that there is a correlation between the depth of the Precordial Depression with the involvement and severity of the anterior descending (LAD) arterial stenosis. However, the results of this study vary and produce various findings related to the involvement of LAD in the IMAEST inferior case.

Background

A number of studies have examined the relationship between coronary artery disease, especially in LAD, with the incidence of inferior Imeest. Some studies, as conducted by Salcedo (1981) and Croft (1982), supported this finding, while other studies such as those conducted by Gibson (1982) did not find significant relationships. Although not all inferior Imeest patients have severe lad disease, there are indications that a number of patients show significant STER depression depth, which can lead to severe presence of lad stenosis.

The importance of the degree of ST depression was expressed by Harakongongse (1983), which shows that the depth of ST depression can function as a potential indicator to assess the involvement of LAD. This study aims to explore further the correlation between the depth of STR depression with the involvement and degree of stenosis in inferior immeest patients.

Research Methods

A total of 60 patients were diagnosed with inferior Imeest in less than 24 hours and showed a picture of Strecordial Depression was treated at the Adam Malik Hajj General Hospital between December 2013 and July 2017. These patients were divided into four groups based on the depth of the precordial depression in the initial ECG they. Bivariate analysis is carried out to evaluate the correlation between the depth of depression with the involvement and severity of the lad stenosis, with p-value <0.05 is considered statistically significant.

Research Result

The results of the bivariate analysis show that the depth of the prepordial depression is correlated with the involvement of LAD (p = 0.01). In addition, the depth of ST depression also shows a correlation with the severity of LAD stenosis (p = 0.01). Patients who have a higher depth of precordial st depression tend to show lesions located in the proximal lad and more complex lesions, although these results are not statistically significant (p = 0.233 and p = 0.102). Through the ROC curve analysis, the Cut-off value for the depth of the Precordial Depression of the LAD is determined at ≥5.15 mm, with a sensitivity of 70% and the specificity of 76.2% (AUC 0.752, 95% CI: 0.620-0.883, P <0.001).

Conclusion

Based on this study, it can be concluded that the greater the depth of the precordial depression, the more likely the involvement of LAD with a significant degree of stenosis (p = 0.01). This shows that the depth of ST depression can be used as an additional indicator in clinical assessment for patients with inferior immeest, especially in determining the involvement of more severe coronary arteries. This discovery adds insight into the pathophysiology of IMAEST and the importance of ECG in rapid and accurate diagnosis.

Implication of the Study

The findings of this study have significant implications for the diagnosis and treatment of patients with acute myocardial infarction. The use of ECG as a diagnostic tool can be improved by incorporating the depth of ST depression as an additional indicator. This can help clinicians to identify patients who are at a higher risk of developing severe coronary artery disease and to provide them with more targeted treatment.

Limitation of the Study

This study has several limitations that need to be addressed. The sample size of the study is relatively small, and the study was conducted in a single hospital setting. Therefore, the findings of this study may not be generalizable to other populations. Additionally, the study only examined the correlation between the depth of ST depression and the involvement of LAD, and did not investigate other potential risk factors for coronary artery disease.

Future Research Directions

Future studies should aim to replicate the findings of this study in larger and more diverse populations. Additionally, studies should investigate the relationship between the depth of ST depression and other risk factors for coronary artery disease, such as hypertension and hyperlipidemia. This can help to provide a more comprehensive understanding of the pathophysiology of IMAEST and to identify potential targets for prevention and treatment.

Recommendations for Clinical Practice

Based on the findings of this study, clinicians should consider incorporating the depth of ST depression as an additional indicator in the diagnosis and treatment of patients with acute myocardial infarction. This can help to improve the accuracy of diagnosis and to provide patients with more targeted treatment. Additionally, clinicians should be aware of the potential limitations of this study and should consider other risk factors for coronary artery disease when making treatment decisions.

Conclusion

In conclusion, this study provides evidence for the correlation between the depth of STE depression and the anterior left artery stenosis in patients with acute myocardial infarction. The findings of this study have significant implications for the diagnosis and treatment of patients with IMAEST and highlight the importance of ECG as a diagnostic tool. Future studies should aim to replicate the findings of this study and to investigate the relationship between the depth of ST depression and other risk factors for coronary artery disease.
Q&A: Correlation between the Depth of STE Depression and the Anterior Left Artery Stenosis in Patients with Acute Myocardial Infarction

Q: What is the significance of the study on the correlation between the depth of STE depression and the anterior left artery stenosis in patients with acute myocardial infarction?

A: The study provides evidence for the correlation between the depth of STE depression and the anterior left artery stenosis in patients with acute myocardial infarction, which can help improve the accuracy of diagnosis and provide patients with more targeted treatment.

Q: What is the relationship between the depth of STE depression and the involvement of LAD in patients with acute myocardial infarction?

A: The study found that the depth of STE depression is correlated with the involvement of LAD in patients with acute myocardial infarction, with a p-value of 0.01.

Q: What is the implication of the study's findings for clinical practice?

A: The study's findings suggest that clinicians should consider incorporating the depth of STE depression as an additional indicator in the diagnosis and treatment of patients with acute myocardial infarction.

Q: What are the limitations of the study?

A: The study has several limitations, including a relatively small sample size and a single hospital setting. Therefore, the findings of the study may not be generalizable to other populations.

Q: What are the potential applications of the study's findings?

A: The study's findings can be applied to improve the accuracy of diagnosis and provide patients with more targeted treatment. Additionally, the study's findings can be used to identify potential targets for prevention and treatment.

Q: What are the potential risks associated with the study's findings?

A: The study's findings suggest that patients with a higher depth of STE depression may be at a higher risk of developing severe coronary artery disease. Therefore, clinicians should be aware of this potential risk and provide patients with more targeted treatment.

Q: What are the potential benefits of the study's findings?

A: The study's findings can provide patients with more accurate diagnosis and treatment, which can improve their outcomes and quality of life.

Q: What are the potential future directions for research on the correlation between the depth of STE depression and the anterior left artery stenosis in patients with acute myocardial infarction?

A: Future studies should aim to replicate the findings of this study in larger and more diverse populations. Additionally, studies should investigate the relationship between the depth of STE depression and other risk factors for coronary artery disease, such as hypertension and hyperlipidemia.

Q: What are the potential implications of the study's findings for public health?

A: The study's findings can have significant implications for public health, as they can help improve the accuracy of diagnosis and provide patients with more targeted treatment. This can lead to improved outcomes and quality of life for patients with acute myocardial infarction.

Q: What are the potential applications of the study's findings for healthcare policy?

A: The study's findings can be used to inform healthcare policy and improve the quality of care for patients with acute myocardial infarction. This can include developing guidelines for the diagnosis and treatment of patients with acute myocardial infarction.

Q: What are the potential benefits of the study's findings for patients with acute myocardial infarction?

A: The study's findings can provide patients with more accurate diagnosis and treatment, which can improve their outcomes and quality of life.

Q: What are the potential risks associated with the study's findings for patients with acute myocardial infarction?

Q: What are the potential implications of the study's findings for the development of new treatments for acute myocardial infarction?

A: The study's findings can have significant implications for the development of new treatments for acute myocardial infarction, as they can help identify potential targets for prevention and treatment.

Q: What are the potential benefits of the study's findings for the development of new treatments for acute myocardial infarction?

A: The study's findings can provide a better understanding of the pathophysiology of acute myocardial infarction, which can lead to the development of new and more effective treatments.

Q: What are the potential risks associated with the study's findings for the development of new treatments for acute myocardial infarction?